Tamp down disease-causing inflammation with fish oil. New research shows that omega-3 fatty acids (the fat found in fish, algae and leafy green vegetables) can help lower inflammation in overweight middle-aged and older adults. Chronic inflammation in the body has been linked to a variety of illnesses, including heart disease, type 2 diabetes, Alzheimer’s disease and rheumatoid arthritis. Supplementing a healthful, nutrient-rich diet with fish oil may offer some protection against these conditions. According to our Cleveland Clinic Wellness experts, taking daily fish oil supplements is a safe and effective way to decrease triglyceride levels, the risk of a subsequent heart attack, and the pain and inflammation of rheumatoid arthritis.